Safety and efficacy of tazarotene foam for the treatment of acne vulgaris
نویسندگان
چکیده
BACKGROUND Tazarotene foam is the first topical retinoid foam approved for the treatment of acne vulgaris. OBJECTIVE To review the safety and efficacy studies of tazarotene foam in the treatment of moderate to severe acne. METHODS Five Phase I safety studies in normal controls are reviewed and two Phase III safety and efficacy studies in patients with moderate to severe acne are reviewed. CONCLUSION Tazarotene foam, 0.1% was effective in the treatment of moderate to severe acne vulgaris with an acceptable tolerability profile. This treatment provides a cosmetically favorable alternative for topical retinoid therapy.
منابع مشابه
Use of tazarotene foam for the treatment of acne vulgaris
Acne vulgaris is a common inflammatory chronic disease of the pilosebaceous unit. It often requires long-term treatment, resulting in increased demand for topical medications that are popular with patients in order to achieve long-term compliance. Tazarotene foam 0.1% is a novel formulation of tazarotene. We review efficacy and tolerability studies of the new formulation, and suggest a possible...
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BACKGROUND Tazarotene is a new 3rd generation topical acetylenic retinoid. It normalizes keratinocyte differentiation, reduces keratinocyte proliferation and decreases expression of inflammatory markers. Tazarotene was approved by U.S.F.D.A. in 1997 for acne vulgaris. OBJECTIVES To evaluate the efficacy and safety of topical tazarotene 0.1% cream in the treatment of facial acne. MATERIALS A...
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Psoriasis, acne vulgaris and photoaging are common conditions. Tazarotene is a pro-drug of tazarotenic acid, a receptor-selective retinoid, which has shown efficacy in the treatment of these disorders. In the treatment of acne vulgaris, it has greater comedolytic activity than the currently available topical retinoids. In psoriasis, tazarotene normalizes keratinocyte differentiation, reverses k...
متن کاملA Comparative Study of Efficacy of once Daily 0.1% Tazarotene and Adapalene Gel for the Treatment of Facial Acne Vulgaris
Background: Acne is a self-limiting chronic inflammatory disorder of pilosebaceous follicles seen among young adults with significant psychological and social impact. Tretinoin which was widely used for many years is being replaced gradually by newer generation agents like Tazarotene and Adapalene which unlike Tretinoin are specific for a subset of retinoic acid receptors. Objectives: To compar...
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عنوان ژورنال:
دوره 6 شماره
صفحات -
تاریخ انتشار 2013